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Nutrilife FR Mensuel Décembre 2021 Nouveauté collagène - Un texte

Consignes générales du client :

Pour notre mensuel envoyés à nos clients (cible:homme/femme plus de 45 ans) nous avons besoin d' un texte mettant en avant les bienfaits du collagène pour la peau. Voici quelques informations à propos du Produit le nom du produit est pour le moment Collagen NuUtricosmetics by Nutrilife. Le collagène est un composant naturel de la peau.
Aide la peau à conserver sa fermeté et son élasticité.
A un effet bénéfique dans l'entretien de la peau
fermeté et élasticité.
+ brochure sur collagène peptan brochure
Vitamine E : La vitamine E contribue à protéger les cellules contre le stress oxydatif Id 160
Collagen peptides are
bioactive directly
in the target tissues
References:
1 Rousselot unpublished study.
2 Aito-Inoue M et al. Transport of a tripeptide, glu-pro-hyp, across the porcine intestinal brush-border membrane. J Pept Sci. 2007; 13: 468-74.
3 Liu X et al. Absorption of hydroxyproline-containing peptides in vascularly perfused rat small intestine in situ. Biosci Biotechnol Biochem 2009; 73: 1741-7.
4 Kawaguchi T et al. Distribution of prolylhydroxyproline and its metabolites after oral administration in rats. Biol Pharm Bull 2012; 35: 422-7.
5 Watanabe-Kamiyama M et al. Absorption and effectiveness of orally administered low molecular weight collagen hydrolysate in rats.
J Agric Food Chemistry 2010; 58: 835-41.
6 Asserin J et al. The effect or oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. J of Cosmetic Dermatol 2015; 14: 291-301.
7 Sibilla S et al. An Overview of the Beneficial Effects of Hydrolysed Collagen as a Nutraceutical on Skin Properties: Scientific Background and Clinical Studies. The Open Nutraceuticals Journal 2015; 8: 29-42.
8 Chung JH et al. Modulation of skin collagen metabolism in aged and photoaged human skin in vivo. J Invest Dermatol 2001; 117: 12 18-24.
Studies with radioactively labelled collagen-derived peptides
show that soon after absorption they enter into target tissues,
such as bone, cartilage, muscle and skin.4 In skin they could be
detected until 14 days after administration.5 Thanks to these
remarkable properties, and their specific bioactivity, studies in
humans have shown that Peptan collagen peptides improve skin
hydration and dermal collagen density, reducing fragmentation of
the dermal collagen network, which is a key
factor in aging.6 In its most recent study,
Rousselot sought to evaluate skin and hair
properties after 90 days of daily supplementation with 5g of bovine
Peptan collagen peptide. This supplementation led to significant
improvements in skin appearance scores, dermal density, and
hair strength in an ethnically diverse Brazilian population.
INTRODUCING DR. JANNE PRAWITT
Dr. Janne Prawitt is the Scientific Director Peptan at Rousselot where she is responsible for the
Nutrition and Health Science portfolio supporting Peptan®, Rousselot’s collagen peptides brand.
As a nutritional scientist by education, she has spent 10 years in academic research in Germany and
France, investigating mechanisms that contribute to the development of metabolic diseases such as
obesity and diabetes. Janne joined Rousselot in 2013, where her work focuses on extending the
scientific evidence for collagen in musculoskeletal health and skin physiology, and on building scientific
ground for the development of new health applications and new products for the global market.
Collagen is naturally present in the body and made up of a unique
combination of amino acids, some of which form very stable peptide bonds
with each other. Those bonds are resistant to breakdown by the digestive
system. Therefore, when orally taking collagen peptides, small bioactive
peptides, in addition to free amino acids, can cross from the intestine into the
bloodstream.2 The peptides also resist further breakdown in the
bloodstream3 and reach connective tissues intact.
Collagen peptides promote
smooth-looking skin
and also benefit hair
This study builds on existing evidence on how oral collagen
supplementation can reduce the signs of skin aging. Sitting under-
neath the skin’s outer epidermis layer, our dermis gives skin strength
and firmness. As people age, the dermis changes structure
because its collagen network breaks up and thins.7 At the same
time skin fibroblast cells slow down production of the matrix that
surrounds them, so that degraded matrix components are not
replaced fast enough.8 This leads to loss of skin elasticity, hydration
and strength, causing visible sagging and wrinkle formation.7,9
However, those changes triggered by aging differ between ethnic
groups. The onset of aging typically begins earlier in less
pigmented compared to more darkly pigmented skin.10,11
One reason is that darkly pigmented skin offers better
UV protection, but the biochemical and physiological
processes involved are complex.
In animals, oral collagen peptide supplementation slows down
aging processes by stimulating collagen production and
hampering the enzyme that breaks down collagen.7,9
In humans, such supplements improve skin hydration,6,12,13,14
elasticity,12,13,14 and dermal collagen density.6,8,14 Rousselot has
tested 10g daily dosages of Peptan from porcine and fish origin in 33 women in Japan and 130 in France, respectively.6
The results, published in 2015, showed increased collagen
density and decreased dermal collagen network fragmentation
after just four weeks of supplementation. In another study,
published in 2015, 60 women in Brazil took 10g of bovine collagen peptides for 90 days.9 This improved dermal collagen
density, skin elasticity and reduced the size of wrinkles and pores.
In addition to benefits on skin, collagen supplements are used to
improve the quality of hair. So far, there is not yet any scientific
evidence proving that collagen is effective. Hair consists of
65-95% protein, with age, hair fibers can be weakend15 making
them easier to break and to appear less shiny. Rousselot has
therefore included the investigation of hair properties in its
recently conducted clinical study. Since hair characteristics differ
according to ethniticy and hair type, it was especially interesting
to investigate this parameter in the study in Brazil, which has an
ethnically diverse population having skin phototype II and III.
In this study, 30 women received 5 g per day of bovine Peptan collagen peptides, and another 30 women a placebo (maltodextrin) supplement for 90 days. The skin properties on their cheeks and
around their nose, eyes and mouth was investigated before starting,
and after 45 and 90 days of supplementation, as were the
characteristics of the hair.
Illustration of skin structure
Line
Wrinkle
Fold
Fat
Collagen
Peptan collagen peptide supplementation is an effective
way of strengthening hair, as well as making skin look
better - this is the conclusion of this new clinical trial1 in
60 healthy Brazilian women, varying in the age of 45 to
60 years old. Those who took Peptan experienced
statistically significant benefits.
Peptan®
Placebo
Baseline 90 days
References:
9 Campos MP et al. An oral supplementation based on hydrolyzed collagen and vitamins improves skin elasticity and dermis echogenicity:
a clinical placebo controlled study. Clinical Pharmacology & Biopharmaceutics 2015; 4: 142.
10 Rawlings AV. Ethnic skin types: are there differences in skin structure and function? Int J Cosmet Sci 2006; 28: 81-95.
11 Hillebrand GG et al. K. The age-dependent changes in skin condition in African Americans, Asian Indians, Caucasians,
East Asians, and Latinos. IFSCC Mag 2001; 4: 259-266.
12 Matsumoto H et al. Clinical effects of fish type I collagen hydrolysate on skin properties. ITE Letters on Batteries, New Technologies and
Medicine 2006; 7: 386-390.
13 Ohara H et al. Improvement in the moisture content of the stratum corneum following 4 weeks of collagen hydrolysate ingestion.
Food Science and Technology Research 2009; 56: 137-145.
14 Inoue N et al. Ingestion of bioactive collagen hydrolysates enhance facial skin moisture and elasticity and reduce facial ageing signs
in a randomized, double-blind, placebo-controlled clinical study. J Sci Food Agric 2016; 96: 40 77-81.
15 Rodríguez MIA et al. Collagen: A review on its sources and potential cosmetic applications. J Cosmet Dermatol 2017; 17: 20-26.
16 Camacho-Bragado GA et al. Understanding breakage in curly hair. British J Dermatol 2015; 173: 10-16.
Collagen peptides reduce
skin wrinkles scores
Peptan® reduces wrinkles around the eye
Representative photographs of the wrinkles of the crow feet
region close to the eye before (baseline) and after
supplementation with either placebo or Peptan.
Changes of the wrinkle score for the crow feet region after
45 and 90 days of supplementation as % compared to baseline (before supplementation). A decrease of the score represents a
decrease in wrinkles. Un texte vendeur qui saura séduire nos lecteurs.

Texte #1
300 mots
Terminé

Pour notre mensuel envoyés à nos clients (cible:homme/femme plus de 45 ans) nous avons besoin d' un texte mettant en avant les bienfaits du collagène pour la peau. Voici quelques informations à propos du Produit le nom du produit est pour le moment Collagen NuUtricosmetics by Nutrilife. Le collagène est un composant naturel de la peau.
Aide la peau à conserver sa fermeté et son élasticité.
A un effet bénéfique dans l'entretien de la peau
fermeté et élasticité.
+ brochure sur collagène peptan brochure
Vitamine E : La vitamine E contribue à protéger les cellules contre le stress oxydatif Id 160
Collagen peptides are
bioactive directly
in the target tissues
References:
1 Rousselot unpublished study.
2 Aito-Inoue M et al. Transport of a tripeptide, glu-pro-hyp, across the porcine intestinal brush-border membrane. J Pept Sci. 2007; 13: 468-74.
3 Liu X et al. Absorption of hydroxyproline-containing peptides in vascularly perfused rat small intestine in situ. Biosci Biotechnol Biochem 2009; 73: 1741-7.
4 Kawaguchi T et al. Distribution of prolylhydroxyproline and its metabolites after oral administration in rats. Biol Pharm Bull 2012; 35: 422-7.
5 Watanabe-Kamiyama M et al. Absorption and effectiveness of orally administered low molecular weight collagen hydrolysate in rats.
J Agric Food Chemistry 2010; 58: 835-41.
6 Asserin J et al. The effect or oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. J of Cosmetic Dermatol 2015; 14: 291-301.
7 Sibilla S et al. An Overview of the Beneficial Effects of Hydrolysed Collagen as a Nutraceutical on Skin Properties: Scientific Background and Clinical Studies. The Open Nutraceuticals Journal 2015; 8: 29-42.
8 Chung JH et al. Modulation of skin collagen metabolism in aged and photoaged human skin in vivo. J Invest Dermatol 2001; 117: 12 18-24.
Studies with radioactively labelled collagen-derived peptides
show that soon after absorption they enter into target tissues,
such as bone, cartilage, muscle and skin.4 In skin they could be
detected until 14 days after administration.5 Thanks to these
remarkable properties, and their specific bioactivity, studies in
humans have shown that Peptan collagen peptides improve skin
hydration and dermal collagen density, reducing fragmentation of
the dermal collagen network, which is a key
factor in aging.6 In its most recent study,
Rousselot sought to evaluate skin and hair
properties after 90 days of daily supplementation with 5g of bovine
Peptan collagen peptide. This supplementation led to significant
improvements in skin appearance scores, dermal density, and
hair strength in an ethnically diverse Brazilian population.
INTRODUCING DR. JANNE PRAWITT
Dr. Janne Prawitt is the Scientific Director Peptan at Rousselot where she is responsible for the
Nutrition and Health Science portfolio supporting Peptan®, Rousselot’s collagen peptides brand.
As a nutritional scientist by education, she has spent 10 years in academic research in Germany and
France, investigating mechanisms that contribute to the development of metabolic diseases such as
obesity and diabetes. Janne joined Rousselot in 2013, where her work focuses on extending the
scientific evidence for collagen in musculoskeletal health and skin physiology, and on building scientific
ground for the development of new health applications and new products for the global market.
Collagen is naturally present in the body and made up of a unique
combination of amino acids, some of which form very stable peptide bonds
with each other. Those bonds are resistant to breakdown by the digestive
system. Therefore, when orally taking collagen peptides, small bioactive
peptides, in addition to free amino acids, can cross from the intestine into the
bloodstream.2 The peptides also resist further breakdown in the
bloodstream3 and reach connective tissues intact.
Collagen peptides promote
smooth-looking skin
and also benefit hair
This study builds on existing evidence on how oral collagen
supplementation can reduce the signs of skin aging. Sitting under-
neath the skin’s outer epidermis layer, our dermis gives skin strength
and firmness. As people age, the dermis changes structure
because its collagen network breaks up and thins.7 At the same
time skin fibroblast cells slow down production of the matrix that
surrounds them, so that degraded matrix components are not
replaced fast enough.8 This leads to loss of skin elasticity, hydration
and strength, causing visible sagging and wrinkle formation.7,9
However, those changes triggered by aging differ between ethnic
groups. The onset of aging typically begins earlier in less
pigmented compared to more darkly pigmented skin.10,11
One reason is that darkly pigmented skin offers better
UV protection, but the biochemical and physiological
processes involved are complex.
In animals, oral collagen peptide supplementation slows down
aging processes by stimulating collagen production and
hampering the enzyme that breaks down collagen.7,9
In humans, such supplements improve skin hydration,6,12,13,14
elasticity,12,13,14 and dermal collagen density.6,8,14 Rousselot has
tested 10g daily dosages of Peptan from porcine and fish origin in 33 women in Japan and 130 in France, respectively.6
The results, published in 2015, showed increased collagen
density and decreased dermal collagen network fragmentation
after just four weeks of supplementation. In another study,
published in 2015, 60 women in Brazil took 10g of bovine collagen peptides for 90 days.9 This improved dermal collagen
density, skin elasticity and reduced the size of wrinkles and pores.
In addition to benefits on skin, collagen supplements are used to
improve the quality of hair. So far, there is not yet any scientific
evidence proving that collagen is effective. Hair consists of
65-95% protein, with age, hair fibers can be weakend15 making
them easier to break and to appear less shiny. Rousselot has
therefore included the investigation of hair properties in its
recently conducted clinical study. Since hair characteristics differ
according to ethniticy and hair type, it was especially interesting
to investigate this parameter in the study in Brazil, which has an
ethnically diverse population having skin phototype II and III.
In this study, 30 women received 5 g per day of bovine Peptan collagen peptides, and another 30 women a placebo (maltodextrin) supplement for 90 days. The skin properties on their cheeks and
around their nose, eyes and mouth was investigated before starting,
and after 45 and 90 days of supplementation, as were the
characteristics of the hair.
Illustration of skin structure
Line
Wrinkle
Fold
Fat
Collagen
Peptan collagen peptide supplementation is an effective
way of strengthening hair, as well as making skin look
better - this is the conclusion of this new clinical trial1 in
60 healthy Brazilian women, varying in the age of 45 to
60 years old. Those who took Peptan experienced
statistically significant benefits.
Peptan®
Placebo
Baseline 90 days
References:
9 Campos MP et al. An oral supplementation based on hydrolyzed collagen and vitamins improves skin elasticity and dermis echogenicity:
a clinical placebo controlled study. Clinical Pharmacology & Biopharmaceutics 2015; 4: 142.
10 Rawlings AV. Ethnic skin types: are there differences in skin structure and function? Int J Cosmet Sci 2006; 28: 81-95.
11 Hillebrand GG et al. K. The age-dependent changes in skin condition in African Americans, Asian Indians, Caucasians,
East Asians, and Latinos. IFSCC Mag 2001; 4: 259-266.
12 Matsumoto H et al. Clinical effects of fish type I collagen hydrolysate on skin properties. ITE Letters on Batteries, New Technologies and
Medicine 2006; 7: 386-390.
13 Ohara H et al. Improvement in the moisture content of the stratum corneum following 4 weeks of collagen hydrolysate ingestion.
Food Science and Technology Research 2009; 56: 137-145.
14 Inoue N et al. Ingestion of bioactive collagen hydrolysates enhance facial skin moisture and elasticity and reduce facial ageing signs
in a randomized, double-blind, placebo-controlled clinical study. J Sci Food Agric 2016; 96: 40 77-81.
15 Rodríguez MIA et al. Collagen: A review on its sources and potential cosmetic applications. J Cosmet Dermatol 2017; 17: 20-26.
16 Camacho-Bragado GA et al. Understanding breakage in curly hair. British J Dermatol 2015; 173: 10-16.
Collagen peptides reduce
skin wrinkles scores
Peptan® reduces wrinkles around the eye
Representative photographs of the wrinkles of the crow feet
region close to the eye before (baseline) and after
supplementation with either placebo or Peptan.
Changes of the wrinkle score for the crow feet region after
45 and 90 days of supplementation as % compared to baseline (before supplementation). A decrease of the score represents a
decrease in wrinkles. Un texte vendeur qui saura séduire nos lecteurs.

VR21-57069 a été choisi pour la rédaction de ce texte.